Product Details

APREPITANT 40MG CAP BLISTER 5

Manufacturer: GLENMARK PHARMACEUTICALS INC

MFG#: 68462058385

PID: 632319

1/BX

$165.72

Limited Quantities
$165.72

Additional Information

Product NameAprepitant 40 mg Capsule (Blister Pack of 5)
ApplicationNeurokinin-1 Receptor Antagonist
Generic Drug NameAprepitant
Mechanism of ActionInhibits substance P binding to NK1 receptor, reducing nausea and vomiting.
Strength40 mg
TypeUnit Dose
Quantity5 Capsules
Recommended Dose40 mg daily for 3 days prior to chemotherapy or surgery.
Side EffectsFatigue, constipation, headache, dizziness.
MetabolismMetabolized by the liver, primarily through CYP3A4 enzymes.
ExcretionExcreted in both urine and feces.
Half-lifeApproximately 9-13 hours.
Container TypeBlister Pack
UsesPrevention of chemotherapy-induced nausea and vomiting (CINV), prevention of postoperative nausea and vomiting (PONV).

Description

Aprepitant 40 mg is a medication used to prevent nausea and vomiting caused by chemotherapy and surgery. It is a selective neurokinin-1 (NK1) receptor antagonist that works by inhibiting the binding of substance P, a neurotransmitter involved in inducing nausea and vomiting, to the NK1 receptor in the brain. This action helps reduce the occurrence of delayed nausea and vomiting following chemotherapy treatment.

Aprepitant is commonly prescribed as part of a combination regimen with other antiemetic medications, such as 5-HT3 antagonists and corticosteroids, for optimal effectiveness in managing chemotherapy-induced nausea and vomiting (CINV). It is also used for postoperative nausea and vomiting (PONV) prevention, especially after major surgeries.

The medication is typically administered in capsule form, with a recommended dose of 40 mg once daily for three days, starting one hour before chemotherapy treatment or surgery. Common side effects of Aprepitant 40 mg include fatigue, constipation, headache, and dizziness. It is important to consult a healthcare provider if any adverse reactions persist or worsen during treatment.

Frequently Asked Questions (FAQs)

The cost of APREPITANT 40MG CAP BLISTER 5 is $$165.72

APREPITANT 40MG CAP BLISTER 5 is manufactured by GLENMARK PHARMACEUTICALS INC.

You can purchase APREPITANT 40MG CAP BLISTER 5 on our website at https://preview_supplies.pipelinemedical.com/Products/Detail/aprepitant-40mg-cap-blister-5-632319

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